Radiff is the program used in radare to identify changes and delta offsets between two binary files. It implements different algorithms to find and show this information:
$ radiff -h
Usage: radiff [-c] [-bgeirp] [file-a] [file-b]
-b bytediff (faster but doesnt support displacements)
-d use gnu diff as backend (default)
-e use erg0ts bdiff (c++) as backend
-p use program diff (code analysis diff)
-s use rsc symdiff
-S use rsc symbytediff
-r output radare commands